Developmental Origins of Pediatric Obesity

Developmental Origins of Pediatric Obesity

1Division of Academic General Pediatrics, Child Development and Community Health, UC San Diego, CA 92093-0927, USA 2Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109-5406, USA 3 Institute of Nutrition and Food Technology (INTA), University of Chile, El Lı́bano 5524, 138-11 Santiago, Chile 4Department of Pediatrics, Catholic University of Chile, Avenida Libertad...

Developmental origins of obesity: programmed adipogenesis.

The metabolic syndrome epidemic, including a marked increase in the prevalence of obesity and gestational diabetes mellitus (GDM) among pregnant women, represents a significant public health problem. There is increasing recognition that the risk of adult obesity is clearly influenced by prenatal and infant environmental exposures, particularly nutrition. This tenet is the fundamental basis of d...

Chemical Exposures: Exploring Developmental Origins of Obesity

In the past 20 years, obesity rates across the developed world have skyrocketed. About one-third of U.S. adults are overweight and another third are obese, according to the National Institute of Diabetes and Digestive and Kidney Diseases. Similarly, more than one-third of U.S. children are overweight or at risk for overweight. The result is a host of health problems for millions of people, incl...

Developmental origins of obesity and non-communicable disease.

Developmental Origins of Obesity - Genetic and Epigenetic Determinants

Background: Childhood obesity is a major public health concern. The importance of genes in development of obesity is evident from twin and family studies. Moreover, epigenetic events in early life may play an important role in obesity etiology. Aim: We aimed to outline and discuss the role of genetic and epigenetic influences on development of obesity in early life from around birth and into ad...